Preliminary Studies towards the Preparation of Reactive 3-Pyrrolin-2-ones in Conjugate Addition Reactions for the Syntheses of Potentially Bioactive 2-Pyrrolidinones and Pyrrolidines
نویسنده
چکیده
Pirrolin-2-onas e 2-pirrolidinonas são subunidades geralmente encontradas na estrutura de vários produtos naturais bioativos e 3-pirrolin-2-onas são valiosos materiais de partida em síntese orgânica devido à habilidade de reagirem como aceptores em reações de adição conjugada. Neste artigo relatamos os resultados iniciais do estudo realizado objetivando as sínteses de 3pirrolin-2-onas reativas em reações de adição conjugada e a preparação de um precursor potencial para a síntese do nootrópico (+/-)-nebracetam.
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تاریخ انتشار 2007